通过控制营养状况评分定义的营养不良与扩散性大B细胞淋巴瘤的预后独立相关,主要是在老年患者身上
Fei Wang1, Luo Lu1, Haoyu Zang1
1Department of Hematology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, People's Republic of China.
Hematology (Amsterdam, Netherlands)
|December 19, 2024
概括
控制营养状况 (CONUT) 评分有效地识别了分散型大B细胞淋巴瘤 (DLBCL) 患者的营养不良. 营养不良显著影响整体存活率,特别是在老年DLBCL患者中.
科学领域:
- 在瘤学瘤学.
- 临床营养学 临床营养学
- 血液学 血液学 血液学
背景情况:
- 控制营养状况 (CONUT) 评分评估营养不良.
- 营养不良与扩散性大B细胞淋巴瘤 (DLBCL) 患者的生存率有关.
研究的目的:
- 评估CONUT得分对DLBCL患者结果的影响.
- 分析CONUT分数对不同年龄和国际预测指数 (IPI) 风险组的影响.
主要方法:
- 对287名新诊断的DLBCL患者的回顾性分析.
- 记录基线CONUT得分,临床数据和生存信息.
主要成果:
- 营养不良患者 (30.7%) 的无进展生存期 (PFS) 和整体生存期 (OS) 显著降低.
- 营养不良是DLBCL患者,特别是老年人中OS的独立预测因素.
- 在低IPI风险组和高IPI风险组中,CONUT评分确定了劣质的OS.
结论:
- 根据CONUT评分评估的营养不良是DLBCL患者结果的独立预测因素.
- 营养不良对生存的影响主要是由它对老年DLBCL患者的影响.
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