关于精神分裂症谱系障碍社会功能因果机制的生命过程视角
Dominika A Osicka1, Jiasi Hao1, Natalia Tiles-Sar1,2
1Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands.
The International journal of social psychiatry
|December 19, 2024
概括
童年创伤,不良的病前调整和感知到的耻辱显著损害了精神分裂症谱系障碍 (SSD) 的社会功能 (SF). 解决这些生命过程因素的干预措施对于改善SSD患者的长期社会康复至关重要.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 社会神经科学是一种社会神经科学.
- 纵向队列研究 纵向队列研究
背景情况:
- 精神分裂谱系障碍 (SSD) 中的社会功能 (SF) 通常被忽视,社会恢复率较低.
- 包括童年逆境在内的生命过程因素与SSD的病后SF损伤有关.
研究的目的:
- 调查影响SSD中的SF机制.
- 检查童年创伤的因果作用,病前调整,感知到的耻辱感,自尊和SSD中的生活质量.
主要方法:
- 对1,057名SSD患者进行长度研究,随访时间为3年和6年.
- 结构方程建模 (SEM) 用于分析因果机制.
- 经过验证的调查问卷评估了诸如童年创伤和感知到的耻辱感等决定因素.
主要成果:
- 在3年随访期间,受损的病前调整直接和负面地影响了SF (β=-.252,p<.001).
- 儿童创伤对3岁后的SF有负面的直接影响 (β=-.087,p=.039) 和显著的间接影响.
- 感知到的耻辱感在3年后对SF产生了负面影响 (β=-.112,p=.008).
结论:
- 病前调整,童年创伤和感知到的耻辱是影响SSD中SF的关键生命过程因素.
- 开发的因果模型为干预策略提供了基础.
- 建议的干预措施应解决童年创伤,病前调整和耻辱,以提高长期的社会结果.
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