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健康科克雷尔在囚禁中的SIFAKAS是否具有异常低的循环皮质醇?
Lydia K Greene1,2, Laura N Ellsaesser3, Elaine E Guevara4
1Duke Lemur Center, Duke University, Durham, NC 27705, USA, lydiakgreene@gmail.com.
概括
囚禁中的Coquerel's sifakas表现出异常低的皮质醇水平和减弱的压力反应,挑战了典型的压力标记假设. 需要进一步的研究来确定这种低皮质醇化是物种特异性的还是被囚禁的结果.
科学领域:
- 灵长类内分泌学
- 野生动物生理学 野生动物生理学
- 应激反应生物学 应激反应生物学
背景情况:
- 皮质醇是野生动物生理压力的标准标志物,通常随着下丘脑-垂体-上腺 (HPA) 轴的激活而增加.
- 事证据表明,被俘的科克雷尔的锡法卡可能不遵循这种模式,尽管存在潜在的压力因素,但皮质醇水平较低.
研究的目的:
- 为了调查低循环皮质醇和对上腺刺激的最小反应是否是健康的囚禁科克雷尔的 sifakas的特征.
- 为了比较克雷尔的sifaka和环尾的压力内分泌特征.
主要方法:
- 管理的上腺皮质激素 (ACTH) 刺激试验或对照试验,以俘可克雷尔的sifaka和环尾.
- 在血清样本中测量了基线和刺激皮质醇度.
- 在17年间,从科克雷尔的sifakas储存的血清样本中测试皮质醇水平.
主要成果:
- 西法卡的基线皮质醇 (0.67μg/dl) 显著低于环尾 (12.53μg/dl).
- 无论是压力处理还是外源性ACTH给药都没有增加西法卡的皮质醇水平,与环尾不同.
- 长期储存的样本显示,sifakas的平均皮质醇水平始终低 (0.49μg/dl),性别,年龄或住房没有变化.
结论:
- 囚禁甲鱼的sifaka表现出独特的内分泌特征,其特点是皮质醇低和抑制的HPA轴反应.
- 这种低皮质化可能是一种特定物种的特征或是被囚禁的慢性压力的后果,可能会影响免疫功能.
- 野生西法卡的比较数据对于区分物种特征和囚禁效应至关重要.
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