牙科随机对照试验的全球地图
Mayara Colpo Prado1, Lara Dotto2, Bernardo Agostini1
1Graduate Program in Dentistry, ATITUS Educação, Passo Fundo, RS, Brazil.
Brazilian dental journal
|December 19, 2024
概括
这项研究分析了2016-2021年期间发表的牙科844项随机对照试验 (RCT). 虽然许多RCT报告了随机化方法和盲目化,但在报告遵守CONSORT等指南时存在显著的变化.
科学领域:
- 牙科研究 牙科研究
- 临床试验中的临床试验.
- 超级研究的研究.
背景情况:
- 随机对照试验 (RCT) 是基于证据的牙科的基础.
- 评估RCT的质量对于可靠的临床决策至关重要.
- 之前对牙科RCT行为和报告的评估是有限的.
研究的目的:
- 综合评估已发表的牙科RCT的行为,报告标准和特征.
- 确定牙科研究成果和国际科学合作的趋势.
- 确定牙科RCT的方法和报告需要改进的领域.
主要方法:
- 在PubMed系统搜索2016年12月31日至2021年12月31日发表的牙科RCT.
- 两个评审人对844项符合条件的英语研究进行了独立选.
- 数据提取包括期刊指标,研究对象,报告细节和行为特征.
主要成果:
- 牙周病是主要的研究领域 (16.35%). 巴西在RCT生产方面领先 (16.59%),而美国拥有最多的国际合作.
- 大多数研究在标题中包括"随机化" (71.92%) 并报告了分配序列生成 (65.88%) 和盲目化 (74.88%).
- 然而,许多研究没有报告CONSORT准则的遵守 (67.89%),随机化类型 (69.31%) 或分配隐藏 (52.37%).
结论:
- 在牙科RCT报告和进行方面存在显著的差异.
- 虽然随机化和盲目化等核心元素经常被报告,但遵守报告准则需要改进.
- 研究结果强调需要加强牙科研究的方法严谨性和透明报告,以支持稳健的临床实践.
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