鼻儿童的症状,生活质量和执行功能
Phoebe K Yu1,2, Kaitlyn Cook3,4, Ignacio E Tapia5
1Department of Otolaryngology, Massachusetts Eye and Ear, Boston.
JAMA otolaryngology-- head & neck surgery
|December 19, 2024
概括
儿童轻度睡眠呼吸障碍与执行功能缺陷有关. 生活质量和症状负担可能有助于识别与这种疾病相关的神经认知问题的儿童.
科学领域:
- 儿科睡眠医学 儿科睡眠医学
- 神经心理学 神经心理学
- 儿童健康研究 儿童健康研究
背景情况:
- 儿童轻度睡眠呼吸障碍 (mSDB) 与神经行为问题和降低生活质量 (QOL) 有关.
- 患有mSDB的儿童的症状负担,QOL和执行功能之间的关系尚不清楚.
- 目前尚不清楚QOL和症状负担是否可以识别患有神经认知功能障碍的儿童.
研究的目的:
- 调查执行功能,QOL和诊断为mSDB的儿童的症状负担之间的关联.
- 确定QOL和症状负担是否可以作为儿科mSDB神经认知缺陷的指标.
主要方法:
- 儿童腺切除术试验对打队列的截面二次分析.
- 包括459名3至12岁的儿童患有mSDB.
- 使用经过验证的仪器评估QOL (OSA-18),症状负担 (PSQ-SRBD) 和执行功能 (BRIEF GEC,GoNoGo测试).
- 在数据分析中使用了部分皮尔森相关性和多重线性回归.
主要成果:
- 在执行功能 (BRIEF GEC) 和QOL (OSA-18) 和症状负担 (PSQ-SRBD) 之间观察到显著的中等相关性.
- 在对共变量进行调整后,较高的OSA-18和PSQ-SRBD得分与较差的执行功能有关 (简要GEC).
- 在GoNoGo测试中,PSQ-SRBD得分也与抑制控制受损和持续的注意力相关.
结论:
- 疾病特异性QOL和症状负担与mSDB儿童的执行功能有显著的关联.
- 这些措施可能是识别有神经认知功能障碍风险的儿童的有价值的工具.
- 研究结果强调了评估儿童群体mSDB的神经认知功能的重要性.
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