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Updated: Jun 4, 2025

TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing
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通过ACSL4介导的H3K9和H3K27过乙化调节SNAIL以驱动TNBC转移

Abhipsa Sinha1, Krishan Kumar Saini1,2, Aakash Chandramouli3

  • 1Division of Cancer Biology, Council of Scientific & Industrial Research-Central Drug Research Institute, Lucknow 226031, India.

Proceedings of the National Academy of Sciences of the United States of America
|December 19, 2024
PubMed
概括

向乙-CoA合成酶4 (ACSL4) 可以减少三阴性乳腺癌 (TNBC) 的转移. 这种代谢酶通过改变基因表达和表观遗传标记来驱动TNBC的传播,提供了一个新的治疗点.

关键词:
在 ACSL4 中使用.一个的子美国TNBC电视台基因素乙化 基因素乙化 基因素乙化转移 转移 转移 转移

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