术后认知功能障碍非药物疗法的比较有效性:系统审查和网络元分析协议
Kexin Wu1,2, Qiongnan Bao3, Jun Huang1
1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
PloS one
|December 19, 2024
概括
这个网络元分析比较了电针,手动针,穿皮电针点刺激和术后认知功能障碍 (POCD) 的认知训练. 它旨在对这些非药物疗法进行排名,以找到最有效的治疗方法来改善手术后的认知功能.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 康复医学 康复医学 康复医学
背景情况:
- 手术后认知功能障碍 (POCD) 是手术后常见的并发症,影响患者的康复.
- 非药物干预措施,如电针 (EA),手动针 (MA),穿皮电针点刺激 (TEAS) 和认知训练 (CT) 在管理POCD方面表现有前途.
- 这些干预措施对POCD的比较有效性仍然不够理解.
研究的目的:
- 进行网络元分析,比较和排名EA,MA,TEAS和CT在治疗POCD方面的有效性.
- 确定最佳的非药物疗法,以维持或改善POCD患者的认知功能.
主要方法:
- 在七个主要数据库中进行了系统的文献搜索,搜索了2000年1月至2023年11月期间发表的研究.
- 两个独立的审查员进行了研究选择和数据提取,重点关注整体认知功能的变化和POCD发病率.
- 双向和贝叶斯网络元分析使用专门的统计软件进行,使用GRADE指南评估证据质量.
主要成果:
- 该分析将比较四种非药物干预治疗术后认知功能障碍的疗效.
- 结果包括整体认知功能的变化和POCD的发病率.
- 偏见风险和证据质量将被严格评估.
结论:
- 这个网络元分析将提供对POCD非药物治疗的排序比较.
- 这些发现将有助于临床医生选择最有效的干预措施来改善术后认知功能.
- 该研究旨在指导基于证据的实践来管理POCD.
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