三种动脉样硬化指数与中风风险之间的显著关联
Xin Wang1, Lili Wu2, Peng Shu3
1Department of Neurosurgery, Beilun District People's Hospital, Ningbo, Zhejiang, China.
PloS one
|December 19, 2024
概括
三种动脉样硬化指数,包括动脉样性血指数 (AIP),卡斯特利风险指数I (CRI-I) 和卡斯特利风险指数II (CRI-II),预测中国老年人中风风险.
科学领域:
- 心血管流行病学心血管流行病学
- 老年医学 老年医学
- 动脉样硬化的生物标志物
背景情况:
- 动脉样硬化是中风的主要危险因素,特别是在老年人群中.
- 确定可靠的中风预测因子对于老年人的预防策略至关重要.
研究的目的:
- 调查三种动脉样硬化指数与中风风险之间的关联.
- 评估血动脉质指数 (AIP),卡斯特利风险指数I (CRI-I) 和卡斯特利风险指数II (CRI-II) 对65岁及以上成年人中风的预测值.
主要方法:
- 利用来自中国健康与退休长度研究 (2011-2015年) 的数据.
- 采用多变量逻辑回归模型和受限立方线来分析中风风险.
- 对三个指数的四分位数和连续变量进行了评估.
主要成果:
- 较高的AIP,CRI-I和CRI-II四分位数与中风风险增加有关 (ORs从1.35到1.52).
- 每单位AIP,CRI-I和CRI-II的增加独立地与更高的中风风险有关 (ORs:分别为1.49,1.06和1.14).
- 在多变量调整后观察到显著的关联.
结论:
- 血动脉生成指数 (AIP),卡斯特利风险指数I (CRI-I) 和卡斯特利风险指数II (CRI-II) 是中风的重要预测指标.
- 这些动脉样硬化指数可能有助于识别中国人口中患中风风险较高的老年人.
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