相关实验视频

Updated: Jun 4, 2025

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
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Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice

Published on: September 25, 2019

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通过表观遗传调节和免疫检查点抑制的组合,增强HBV特异性T细胞反应

Melanie Urbanek-Quaing1,2,3,4, Yin-Han Chou1,3,4,5, Manoj Kumar Gupta3,5

  • 1Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.

Hepatology (Baltimore, Md.)
|December 19, 2024
PubMed
概括

德西他 (DAC) 和抗编程细胞死亡-1抗体 (αPD-L1) 的组合在体外增强了B型肝炎病毒 (HBV) 特定的T细胞反应. 这种方法可以通过逆转表观遗传变化,帮助恢复慢性HBV感染的免疫功能.

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