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相关概念视频

Three Developmental Domains01:29

Three Developmental Domains

Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...

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相关实验视频

Updated: Jun 2, 2026

Cortical Source Analysis of High-Density EEG Recordings in Children
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新生儿大脑中国家依赖的互联网功能连接的发展,来自于正在发展的人类连接组项目.

Zhiyong Zhao1, Ruolin Li2, Yihan Wu3

  • 1Department of Radiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.

Developmental cognitive neuroscience
|December 19, 2024
PubMed
概括

婴儿的大脑连接随着年龄的增长而动态发展,从弱连接到强连接状态的过渡. 过早出生会改变这种动态的功能连接发展,影响大脑网络的成熟.

关键词:
在 DHCP 中, DHCP 是 DHCP 的代码.动态功能连接的动态功能连接新生儿新生儿新生儿过早生育的孩子.休息状态网络网络的静止状态.国家依赖的国家依赖.

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Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging
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相关实验视频

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科学领域:

  • 神经科学是一个神经科学.
  • 发育神经科学的发展神经科学.
  • 脑部成像 脑部成像

背景情况:

  • 休息状态网络在婴儿期早期就会出现,但它们与年龄相关的变化和动态变化仍然不清楚.
  • 了解功能连接动态对于评估早期大脑发育至关重要.

研究的目的:

  • 调查期和早产婴儿的动态功能网络连接 (dFNC).
  • 评估dFNC的年龄相关变化以及早产对大脑网络动态的影响.

主要方法:

  • 利用了来自开发人类结合体项目 (dHCP) 的244名终身婴儿和36名早产婴儿 (37-43周校正年龄) 的休息状态功能性MRI (fMRI) 数据.
  • 分析了动态功能网络连接 (dFNC) 并确定了不同的连接状态 (弱连接状态I,强连接状态II).

主要成果:

  • 妊娠年龄 (GA) 和产后年龄 (PNA) 不同地影响了随时间变化的功能连接 (FNC) 变化的变异性,特别是在高阶关联网络中.
  • 过早分娩显著减少了FNC变化中的这些差异.
  • 婴儿在弱连接状态 (I状态) 中花费了更多时间,更长的持续时间和过渡与GA和PNA负相关.
  • 过早出生的婴儿在较弱连接状态中表现出较长时间的时间,而不是按期出生的婴儿.

结论:

  • 早期的大脑发育涉及功能网络连接的状态依赖动态.
  • 随着婴儿的年龄增长,大脑网络逐渐成熟,成为一个更灵活的系统,具有更强的连接.
  • 过早出生会破坏动态功能连接的典型发育轨迹,导致长时间的网络相互作用较弱.