纽约野生动物:新兴病原体的分布和遗传多样性
Corinne L Conlon1, Julia P Brigandi1, Jacqueline L Frair1
1SUNY-ESF, State University of New York College of Environmental Science and Forestry, Environmental Biology, 1 Forestry Drive, Syracuse, New York 13210.
The Journal of parasitology
|December 19, 2024
概括
一种欧洲的 Echinococcus multilocularis 变种正在北美扩散,在纽约发现了新的病例. 这种寄生虫在人类中构成膜球菌病的风险,需要积极监测.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 动物传染病流行病学
- 分子遗传学分子遗传学
背景情况:
- Echinococcus 是一个具有全球意义的寄生虫属.
- 两个物种, Echinococcus granulosus sensu lato 和 Echinococcus multilocularis,是北美本土的.
- 由于欧洲变种的引入, Echinococcus multilocularis 正在导致北美地区的流行病学转变.
研究的目的:
- 在纽约州调查 Echinococcus multilocularis 的存在和遗传谱系.
- 评估动物传染病的风险,并为公共卫生措施提供信息.
主要方法:
- 在纽约州 (2019-2023) 的最终宿主中进行寄生虫监测.
- 使用线粒体标记物的植物遗传学分析.
- 微卫星基因型鉴定 (EmsB标志物).微卫星基因型鉴定.
主要成果:
- 发现了八个 Echinococcus multilocularis 的检测,样本流行率为 8.3%.
- 遗传学分析证实,纽约的分离物属于欧洲血统,与斯洛伐克和波兰的分离物聚集在一起.
- 在纽约发现了多种E. multilocularis基因型,其中包括一个与北美西部分离的基因型.
结论:
- 这些发现表明,欧洲 Echinococcus multilocularis 变种从欧洲向纽约引入了一种或多种独特的变种.
- 北美复杂的流行病学需要进一步的监测,以评估动物性传染风险.
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