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在Graves疾病中,医疗治疗的管理方面
Rutu Shah1, Samantha E Adamson1, Sina Jasim1
1Division of Endocrinology, Metabolism and Lipid Research, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.
概括
抗甲状腺药物 (ATD) 是对格雷夫斯病 (GD) 的安全有效的医疗治疗方法. 长期使用ATD,特别是与升高的thyrotropin受体抗体,提供比手术或放射性更高的缓解率.
科学领域:
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 格雷夫斯病 (GD) 是甲状腺功能障碍的主要原因.
- 目前的GD治疗包括抗甲状腺药物 (ATD),放射性和手术.
研究的目的:
- 审查格雷夫斯病的医疗管理.
- 专注于抗甲状腺药物 (ATD) 治疗GD.
主要方法:
- 在PubMed. 的文献综述.
- 包括关于GD管理,ATD和相关条件的研究和评论.
主要成果:
- 医疗管理包括ATDs,β-阻断剂,葡萄糖皮质类药物和剂.
- 在美国,ATD是首选的初始GD治疗方法.
- 在怀孕期间和特殊情况下长期使用ATD是安全的,并且耐受良好.
- 甲状腺功能测试和甲状腺受体抗体水平对于监测和治疗决策至关重要.
结论:
- 用ATD治疗GD的医疗管理是安全有效的.
- 长期使用ATD (>24个月) 是手术或放射性的可行替代方案,用于在甲状腺素受体抗体升高的患者中实现缓解.
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