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Updated: Jun 13, 2025

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癌症中的线粒体DNA激活cGAS-STING通路:机制和治疗含义

Lintao Xia1, Xiuli Yan2, Hui Zhang1

  • 1Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Biochimica et biophysica acta. Reviews on cancer
|December 19, 2024
PubMed
概括

线粒体DNA (mtDNA) 在癌症中激活免疫路径,促进炎症和细胞死亡. 针对mtDNA泄漏提供了新的策略,将冷瘤转化为热瘤,以加强癌症治疗.

关键词:
癌症 癌症 癌症 癌症天生的免疫系统天生的免疫系统.线粒体DNA DNA 线粒体cGAS-STING 的使用情况.

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