与VDD节奏相比,适应性心房支对心脏再同步治疗接受者的效果:一个随机交叉研究
Luca Donazzan1, Francesca Bulian1, Massimiliano Maines2
1Department of Cardiology, San Maurizio Regional Hospital, Bolzano, Italy.
American heart journal
|December 19, 2024
概括
在CRT除器患者中,速度适应性心房支 (DDDR) 与VDD节奏相比没有功能性或心声学上的优势. 建议最大限度地提高内在鼻节律传感,以获得最佳的患者反应.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 心脏衰竭管理的管理
背景情况:
- 心脏再同步疗法 (CRT) 是一种关键的心力衰竭治疗方法,但最佳节奏模式的选择仍在争论中.
- 这项研究比较了CRT除器患者的DDR (速度适应性心房支持) 和VDD节奏.
研究的目的:
- 评估DDDR与VDD节拍模式对功能能力和心声回声结果的影响.
- 为了确定是否速度适应性心房支在CRT患者中比VDD节奏提供了优势.
主要方法:
- 一个多中心,双盲,交叉试验,涉及26名带有CRT除器的鼻节律患者.
- 患者被随机分配到DDDR或VDD步调中,每个6个月.
- 评估的结果包括6分钟步行测试 (6MWT) 距离和心声回声学参数.
主要成果:
- 在DDDR和VDD节拍模式之间没有观察到6MWT距离或心声回声参数的显著差异.
- 节奏模式的顺序并没有显著影响结果.
- 基线步行距离和研究持续时间与随访步行距离正相关.
结论:
- 速度适应性心房支 (DDDR) 在这个患者队列中没有在VDD节奏上提供明显的优势.
- 研究结果表明,在CRT设备编程中,优先考虑最大化内在鼻节律传感.
相关概念视频
Disturbances in Heart Rhythm
898
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
898
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
775
Class IV antiarrhythmic drugs, such as verapamil and diltiazem, block calcium channels. They primarily affect the heart, slowing the conduction in calcium-dependent tissues like the SA and AV nodes. These drugs manage reentrant supraventricular tachycardia (SVT) and reduce ventricular rate in atrial flutter/fibrillation.
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
775


