便秘对下尿路功能和治疗反应的影响,非单一症状尿尿症患者的治疗反应
Yi-Ju Chou1, Stephen Shei-Dei Yang2,3
1Division of Urology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 16F, #289, Chienkuo Road, Xindian, New Taipei, 23142, Taiwan.
BMC urology
|December 20, 2024
概括
患有非单症状夜间尿液浸泡症 (NMNE) 的儿童的便秘与更严重的白天尿路症状有关,需要增加药物治疗. 然而,对于患有或没有便秘的NMNE患者来说,治疗反应时间与NMNE患者相似.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 胃肠病学 胃肠病学
- 下尿道功能障碍 下尿道功能障碍
背景情况:
- 非单一症状的夜间尿泡症 (NMNE) 是一个常见的儿科疾病.
- 便秘与NMNE的同时发生可能会影响下尿路功能和治疗结果.
- 了解这些协会对于有效的管理策略至关重要.
研究的目的:
- 调查NMNE儿科患者之间的下泌尿道功能差异,比较有便秘和没有便秘的儿科患者.
- 评估和比较这两组NMNE患者的治疗反应.
主要方法:
- 从尿尿注射数据库中对128名儿科NMNE患者 (年龄≥5岁) 的回顾性分析.
- 使用了关于便秘的罗马IV标准,功能障碍排泄得分问卷 (DVSS),排泄/尿道日记,以及带有空气后残留 (PVR) 的尿液流量计.
- 在患有便秘和没有便秘的NMNE患者之间比较下尿路功能参数和治疗结果.
主要成果:
- 患有便秘的NMNE患者在白天失禁,急迫性和持有机动方面表现出显著更高的DVSS得分.
- 两组之间没有观察到白天空置体积或频率的显著差异.
- 便秘组需要更多的药物治疗尿尿症,但便秘不会影响实现部分或完全治疗反应的时间.
结论:
- 在儿童NMNE患者中,便秘与更严重的白天下尿路症状有关.
- 这些患者可能需要多种药物的组合来有效治疗尿.
- 尽管症状严重程度和药物需求增加,但在NMNE患者中,如果适当管理,便秘的治疗反应的时间与没有便秘的患者相似.
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