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通过lmCen-/-寄生虫对IRF7介导的I型干扰素反应进行下调,这对于保护性免疫来说是必要的

Telly Sepahpour1, Jalal Alshaweesh2, Nazli Azodi1

  • 1Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.

NPJ vaccines
|December 20, 2024
PubMed
概括

一种新的活体减弱疫苗对莱什曼病有希望. 消除I型干扰素反应对于疫苗诱导针对Leishmania donovani感染的保护性免疫是至关重要的.

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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
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