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食物过敏的初级预防:超越早期引入
Edmond S Chan1, Elissa M Abrams2,3, Douglas P Mack4,5
1Division of Allergy, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, BC, Canada. EChan5@cw.bc.ca.
概括
早期引入和定期食用过敏性食物对于预防婴儿食物过敏至关重要. 犹不决的家庭可以在诊所寻求指导引入,对那些没有反应的人进行口服免疫疗法.
科学领域:
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
- 过敏学 过敏学
背景情况:
- 食物过敏的患病率有所增加,可能是由于过敏原食品的推迟引入.
- 目前的婴儿养指南强调在4-6个月左右早期引入过敏原食物.
- 对引入致过敏食品的犹可能会导致食物过敏率的上升.
研究的目的:
- 突出定期,持续摄入致敏食品对于预防食物过敏的重要.
- 解决牛奶配方 (CMF) 暴露在预防牛奶过敏 (CMA) 中的作用.
- 为管理犹不决消费过敏性食物的婴儿和那些未能进行初级预防的婴儿提供指导.
主要方法:
- 审查当前的婴儿养指南和过敏预防策略.
- 对过敏原食品的早期和间歇性暴露的影响分析.
- 对预防食物过敏的临床管理途径的讨论.
主要成果:
- 定期摄入,而不仅仅是早期引入,对于预防食物过敏至关重要.
- 间歇性牛奶配方 (CMF) 暴露会增加牛奶过敏 (CMA) 的风险,而定期暴露是保护性的.
- 初级保健诊所可以为犹不决的家庭提供食物.
- 对于未能进行初级预防的婴儿,建议向过敏学家推早期婴儿口服免疫疗法 (OIT).
结论:
- 持续消费过敏性食物对于预防食物过敏至关重要.
- 结构化的引入和管理是风险婴儿的关键.
- 口服免疫疗法 (OIT) 是耐火病例的一个可行的选择.
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