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Updated: Jun 4, 2025

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"QuickDASH"寻找与肩膀关节炎相关的独特基因和生物过程:一个前性病例控制研究

Samuel J Lynskey1,2, Stephen D Gill3,4,5,6, Sean L McGee7

  • 1Department of Orthopaedic Surgery, Geelong University Hospital, Geelong, Australia. Samuel.lynskey@svha.org.au.

BMC research notes
|December 20, 2024
PubMed
概括

肩部骨关节炎 (OA) 涉及炎症和应激反应基因,与部和膝盖OA不同. 基因表达的变化与肩膀功能下降相关,为OA分子基础提供了新的见解.

关键词:
基因表达 基因表达 基因表达骨关节炎是一种骨关节炎.肩膀 肩膀 在肩膀上转录组 转录组就是一个转录组.文字转录学 (Transcriptomics) 是一个学科.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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