肥胖或超重儿童的动脉内心介质厚度值:一个元分析
Jean-Baptiste Moretti1,2, Alexandre Korban3, Émilie Alchourron1,2
1University of Montreal, Montreal, QC, Canada.
European radiology
|December 20, 2024
概括
超重或肥胖的儿童表现出动脉内心介质厚度 (IMT) 的增加,这是早期动脉样硬化的标志. 这一元分析证实,肥胖儿童的IMT明显高于使用超声波技术的正常体重同龄人.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 血管超声波是指血管超声波.
- 公共卫生 公共卫生
背景情况:
- 动脉内心介质厚度 (IMT) 作为早期动脉样硬化的非侵入性超声波指标.
- 儿童肥胖是一个日益严重的公共卫生问题,具有潜在的长期心血管影响.
研究的目的:
- 系统地审查和分析已公布的关于超重或肥胖儿童IMT差异的数据,与正常体重对照相比.
- 评估超重和肥胖对儿科患者IMT的影响.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 包括使用正常体重控制和IMT测量通过B模式或射频 (RF) 回声追踪技术的队列研究.
- 利用世界卫生组织对儿童肥胖的增长标准定义,并从创立到2024年2月搜索主要科学数据库.
主要成果:
- 对15个B模式和2个射频回声跟踪研究的分析显示,超重/肥胖儿童的IMT显著增加.
- 使用B模式的平均IMT高出0.041mm (95%CI:0.0310.052),使用射频技术的平均IMT高出0.045mm (95%CI:0.0290.062).
结论:
- 这一元分析表明,与正常体重儿童相比,肥胖儿童的动脉内心介质厚度显著增加.
- 研究结果强调IMT作为亚临床动脉样硬化在儿科肥胖症中的生物标志物的实用性,无论测量技术如何.
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