在接受心脏导管手术的成年人中使用CRISP修饰器:单一中心体验
Kathryn P Reynolds1, Ernesto Mejia2, Natalie Soszyn2
1Heart Institute, Children's Hospital of Colorado, University of Colorado, Aurora, CO, USA. kpreynolds09@gmail.com.
儿科导管风险评分 (CRISP) 可以预测心脏导管治疗的成年人的不良事件. 将成人特异性因素添加到CRISP得分中,可以提高该人群中不良事件的预测准确度.
科学领域:
- 心脏病学 心脏病学
- 医疗信息学 医疗信息学
背景情况:
- 儿科导管风险评分 (CRISP) 是一个验证的工具,用于预测儿科心脏导管中的不良结果.
- 它的适用性和预测准确性在成年人中,特别是那些患有先天性心脏病的人中,需要进一步研究.
研究的目的:
- 评估CRISP得分在预测心脏导管治疗的成年人不良事件 (AE) 的有效性.
- 确定是否结合特定的成年修饰剂 (NYHA类>2,之前的胸口切除>2,BMI>30) 提高了CRISP得分在这个人口群体中对AE的预测能力.
主要方法:
- 在2016年11月至2021年11月期间接受心脏导管治疗的401名成人患者 (>18岁) 的回顾性分析.
- 基线CRISP得分与修改CRISP得分 (包括成人修改剂) 的比较,用于使用ROC分析预测AEs.
主要成果:
- 总共有27个AE (6.7%) 被观察到.
- 较高的基线CRISP得分与AE风险增加显著相关 (p=0.004),AUC为66%.
- 修改后的CRISP评分也显示了与AE的显著关联 (p=0.01),AUC为64%,表明预测性能与原始评分相似.
结论:
- 即使添加了成人特异性修饰剂,CRISP得分也表现出与预测心脏导管治疗的先天性心脏病成年人的不良事件的能力相似.
- 拟议的成人修饰器可以很容易地集成到现有的CRISP评分框架中.
- 这些发现表明,CRISP得分仍然是成年心脏导管患者风险评估的宝贵工具.
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