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Translesion DNA Polymerases

Translesion DNA Polymerases

Translesion (TLS) polymerases rescue stalled DNA polymerases at sites of damaged bases by replacing the replicative polymerase and installing a nucleotide across the damaged site. Doing so, TLS allows additional time for the cell to repair the damage before resuming regular DNA replication.
TLS polymerases are found in all three domains of life - archaea, bacteria, and eukaryotes. Of the different classes of TLS polymerases, members of the Y family are fitted with specialized structures that...

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Updated: May 5, 2026

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions

Published on: May 28, 2017

[MMLV逆转录酶是分子生物学的一个重要工具]

Eva Lopez¹, Coralie Valle¹, Bruno Coutard¹

¹Unité des Virus émergents (UVE : Aix-Marseille Univ, Università di Corsica, Corte, IRD 190, Inserm 1207, IRBA), France.

Virologie (Montrouge, France)

|December 20, 2024

概括

莫洛尼小鼠白血病病毒 (MMLV) 逆转录酶是分子生物学中的一个关键酶. 优化提高了它在日常实验室诊断和生物技术应用中的性能.

科学领域:

酶学是一种酶学.
分子生物学分子生物学
病毒学病毒学

关键词:

分子生物学分子生物学蛋白质工程工程蛋白质工程反向转录酶的使用

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Last Updated: May 5, 2026

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions

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