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Updated: Jul 6, 2026

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在小鼠扩展皮肤模型中,对与皮肤生长相关的枢纽基因和微环境特征的全面分析

Yinmin Wang1, Wenxiao Qi2, Shun Yu3

  • 1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

Frontiers in immunology
|December 20, 2024
PubMed
概括

识别Notch1和Tpm1等关键基因可以预测组织扩张期间皮肤再生的成功. 这项研究有助于了解改善皮肤移植结果的细胞机制.

关键词:
核心基因 核心基因 核心基因巨细胞 (MC) 是一种巨细胞.微观环境是一个微观环境.皮肤再生 皮肤再生组织扩张 组织扩张

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...