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吸烟对肠道微生物失调的影响:一个结构化的文献综述

Emmanuel Edoghogho Imade^1,2, Nosa Omoregbe Obayagbona³

¹Department of Microbiology, Faculty of Life Sciences, University of Benin, Benin City, Nigeria.

Gut microbiome (Cambridge, England)

|December 20, 2024

概括

吸烟显著改变了肠道微生物群,增加了诸如 Bacteroidetes 这样的有害细菌,减少了有益的 Firmicutes. 由于与炎症的联系,吸烟者的这种肠道失调有严重的公共卫生影响.

科学领域:

微生物组研究的研究.
公共卫生公共卫生
胃肠病学胃肠病学

背景情况:

肠道微生物群 (GM) 在人类健康中起着至关重要的作用.
生活方式因素,如吸烟,可以破坏转基因平衡,导致肠道疾病 (GMD).
了解香烟烟雾对转基因疾病的影响对于公共卫生至关重要.

研究的目的:

审查CS对活跃吸烟者与非吸烟者的GMD的影响.
评估CS诱导的GMD对公众健康的影响.

主要方法:

在CINAHL,Medline和PubMed进行了系统的文献搜索.
研究是按照PRISMA 2020指南进行选择和选的.
关键评估技能计划 (CASP) 工具评估了研究质量,最终审查中包括了5项研究.

主要成果:

CS对肠道微生物的比例产生负面影响,改变了Firmicutes/Bacteroidetes (Fir/Bac) 的比率.
与非吸烟者相比,吸烟者表现出较高的细菌菌群和较低的菌菌群.
在吸烟者中丰富的特定细菌 (例如,Bacteroidales,Ruminococcus) 与炎症生物标志物相关,而在非吸烟者中发现的其他细菌 (例如,Eubacterium,Roseburia) 显示出负相关性.

结论:

吸烟会诱导肠道失调,其特点是微生物群体的特定变化.
观察到的肠道微生物组成的变化与炎症标志物增加有关.
由CS引发的转基因疾病对公众健康有重大影响,需要进一步调查和干预.

关键词:

细菌菌体 (Bacteroidetes) 是一种细菌体.卡斯普工具是CASP的工具.坚固的树根坚固的树根普里斯马的指导方针是什么公共卫生影响公共卫生影响

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