在迷幻药下半球和侧面化 (HEALS):一种关于迷幻药在大脑中的作用的新假设
1Center for Psychedelic Drug Research and Education, College of Social Work, The Ohio State University, Columbus, OH, USA.
Journal of psychopharmacology (Oxford, England)
|December 20, 2024
概括
这项研究引入了半球和侧面化在迷幻药下 (HEALS) 模型,提出迷幻药可以从左向右逆转大脑半球的主导地位. 这种转变可能解释了在改变意识状态期间的各种认知和情绪变化.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
背景情况:
- 目前的迷幻作用模型侧重于背腔 - 腹腔和前后脑轴.
- 侧轴和半球相互作用在理解迷幻效应时经常被忽视.
研究的目的:
- 提出一种新型的迷幻作用模型,HEALS (迷幻药下半球和侧面化).
- 通过半球层次的逆转来解释意识的改变状态 (ASCs).
主要方法:
- 审查现有的神经成像证据,用于半球横向化在迷幻药下.
- 与半球角色对比认知和情绪功能 (注意力,社会智力,创造力,语言).
主要成果:
- HEALS模型假设在迷幻药下,典型的左半球主导地位发生了逆转.
- 有证据表明,在ASC期间,右半球从左半球抑制中释放出右半球.
- 迷幻药物和其他ASC中的现象可能源于非典型的半球化导致右半球占主导地位.
结论:
- HEALS模型通过结合横轴来提供对迷幻作用的新视角.
- 在ASC期间右半球占主导地位可能是显著认知和情绪转变的基础.
- 对半球相互作用的进一步研究对于理解意识和迷幻效应至关重要.
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