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Updated: Jun 4, 2025

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骨质疏松素调节的变化与乳腺癌相关的母细胞种群

О Mushii1, А Pavlova1, V Bazas2

  • 1R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine.

Experimental oncology
|December 20, 2024
PubMed
概括

骨质疏松素 (OP) 表达与巨细胞 (MC) 活动和乳腺癌 (BCa) 攻击性相关. 这种关系表明OP和MC可以预测瘤进展,并告知治疗策略.

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Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
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