三种营养指数对炎症性肠病患者疾病活性的预测值
Zhuoyan Chen1, Liuwei Zeng1, Weimin Cai1
1Department of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, P.R. China.
Annals of medicine
|December 20, 2024
概括
营养不良,通过PNI,GNRI和CONUT评分进行评估,独立预测炎症性肠病 (IBD) 活动. 老年营养风险指数 (GNRI) 在本研究中显示出最高的预测值.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 内部医学 内部医学
背景情况:
- 在患有炎症性肠病 (IBD) 的患者中,营养不良很常见.
- 营养不良对IBD疾病活动的预测能力以前没有被探索.
- 这项研究调查了IBD患者的营养状况和疾病活性之间的关联.
研究的目的:
- 探索患有炎症性肠病 (IBD) 的患者营养不良和疾病活动之间的关联.
- 为了确定可以预测IBD疾病活动的营养指数.
主要方法:
- 从2011年到2022年,对1006名IBD患者进行了回顾性研究.
- 使用预后营养指数 (PNI),老年营养风险指数 (GNRI) 和控制营养状况 (CONUT) 评分来评估营养不良.
- 后勤回归和接收器运行特征 (ROC) 曲线分析被用来评估预测因素和预测性能.
主要成果:
- 营养不良的发生率为16.9% (PNI),72.1% (GNRI) 和75.6% (CONUT).
- 确定PNI,GNRI和CONUT是IBD疾病活动的独立风险因素.
- 在三个指数中,GNRI的预测值是最高的;结合指数提高了C反应蛋白的预测能力.
结论:
- 根据PNI,GNRI和CONUT的指标,营养不良是IBD疾病活动的独立风险因素.
- 营养评估在预测IBD患者的疾病活性方面发挥着至关重要的作用.
- 在IBD中,GNRI是评估营养不良相关风险的宝贵工具.
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