关节骨折单位的环境污染以及对死亡率和术后妄想的影响:一种抑制作用?
Chika Edward Uzoigwe1, Rana Muhammad Anss Bin Qadir2, Ahmed Daoub3
1Harcourt House, Sheffield, United Kingdom.
PloS one
|December 20, 2024
概括
大多数英国关节骨折单位都超过了世界卫生组织 (WHO) 对细颗粒物 (PM2.5) 和二氧化的污染限值. 较高的污染暴露与老年患者妄风险的降低有关,但与死亡率无关.
科学领域:
- 环境健康 环境健康
- 老年医学 老年医学
- 流行病学 流行病学
背景情况:
- 越来越多的证据将环境污染与不良健康结果联系在一起.
- 世界卫生组织 (WHO) 更新了PM2.5,PM10和二氧化暴露的指导方针.
- 目前英国的标准超过了世卫组织的建议,这给医疗机构带来了挑战.
研究的目的:
- 确定英国部骨折中心中超过世卫组织污染限值的比例.
- 调查环境污染物水平对30天死亡率和老年关节骨折患者手术后妄想的影响.
主要方法:
- 利用了英国国家关节骨折数据库和Defra数据.
- 对骨骨折治疗单位的PM2.5,PM10和二氧化的估计年平均暴露.
- 相关的污染物水平与所有原因的30天死亡率和术后狂妄症的发生率.
主要成果:
- 96%的关节骨折单位位于超过世卫组织PM2.5限值的地区.
- 显著的比例超过了世卫组织PM10 (14.8%) 和二氧化 (63%) 的限值.
- 在超过和不超过世卫组织限值的单位之间,没有观察到30天死亡率的显著差异.
- 较高的PM10和二氧化水平与手术后妄想风险降低相关 (RR分别为0.89和0.92).
结论:
- 大多数治疗关节骨折患者的英国医疗机构都超过了世卫组织的空气污染指南.
- 超过世卫组织污染限值并没有对关节骨折患者的30天死亡率产生负面影响.
- 在污染较高的地区, Delirium 发病率降低表明存在潜在的抑郁效应,需要进一步调查.
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