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Updated: Jun 4, 2025

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

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一种细菌甲基转移酶,启动生物合成,是一种有吸引力的抗ESKAPE可用药途径

Zhi Su1,2, Weizhen Zhang3, Yu Shi1

  • 1Key Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.

Science advances
|December 20, 2024
PubMed
概括

研究人员定义了在ESKAPE病原体中启动生物合成的BioC酶. 无活化BioC使细菌成为生物辅食素,揭示了其作为药物点的重要作用和潜力.

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