Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Vestibular System01:29

The Vestibular System

39.3K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
39.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A novel chimeric peptide binds MC3T3‑E1 cells to titanium and enhances their proliferation and differentiation.

Molecular medicine reports·2013
Same author

Fast trabecular bone strength predictions of HR-pQCT and individual trabeculae segmentation-based plate and rod finite element model discriminate postmenopausal vertebral fractures.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2013
Same author

Biological activities and corresponding SARs of andrographolide and its derivatives.

Mini reviews in medicinal chemistry·2013
Same author

The prognostic value of MGMT promoter methylation in Glioblastoma multiforme: a meta-analysis.

Familial cancer·2013
Same author

Understanding the structure and mechanism of formation of a new magnetic microbubble formulation.

Theranostics·2013
Same author

Analysis of IL-17 gene polymorphisms in Chinese patients with dilated cardiomyopathy.

Human immunology·2013

相关实验视频

Updated: Jun 4, 2025

A Unified Methodological Framework for Vestibular Schwannoma Research
08:43

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

7.4K

炎症蛋白和前置神经炎症:孟德尔的随机化研究

Yu He1,2, Tao Guo1,2, Tianrong Dai1,2

  • 1Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Medicine
|December 20, 2024
PubMed
概括

这项研究调查了91种炎症蛋白和前庭神经炎 (VN) 之间的因果关系. 较低的eotaxin和单细胞化疗蛋白-2水平,以及较高的T细胞糖蛋白CD5水平,与VN风险有因果关系.

科学领域:

  • 免疫学 免疫学 免疫学
  • 遗传学 是一个遗传学.
  • 神经学 神经学

背景情况:

  • 静脉神经炎 (VN) 是一种经常与炎症过程相关的疾病.
  • 了解涉及VN病变的特定炎症因素对于开发有效治疗是至关重要的.

研究的目的:

  • 进行全面的门德尔随机化分析,以确定91种炎症蛋白和前置神经炎之间的因果关系.
  • 识别特定的炎症蛋白质,这些蛋白质可能作为VN风险的上游决定因素.

主要方法:

  • 利用公开可用的遗传数据进行孟德尔随机化分析.
  • 使用逆方差加权 (IVW) 评估了91种炎症蛋白和VN之间的因果关系.
  • 进行了全面的敏感性分析,以确保调查结果的稳定性和可靠性.

主要成果:

  • 确定了三种具有对VN显著因果影响的炎症蛋白质.
  • 毒素水平与VN的风险降低有关 (OR=0.7113,P=0.0331).
  • 单细胞化疗蛋白-2水平与VN风险降低有关 (OR=0.8535,P=0.0418).
  • T细胞表面糖蛋白CD5水平与VN的风险增加相关 (OR=1.3969,P=0.0437).

更多相关视频

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
00:06

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

Published on: August 28, 2019

5.1K
Long-term Sensory Conflict in Freely Behaving Mice
06:12

Long-term Sensory Conflict in Freely Behaving Mice

Published on: February 20, 2019

6.6K

相关实验视频

Last Updated: Jun 4, 2025

A Unified Methodological Framework for Vestibular Schwannoma Research
08:43

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

7.4K
Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
00:06

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

Published on: August 28, 2019

5.1K
Long-term Sensory Conflict in Freely Behaving Mice
06:12

Long-term Sensory Conflict in Freely Behaving Mice

Published on: February 20, 2019

6.6K

结论:

  • 毒素,单细胞化疗蛋白-2和T细胞表面糖蛋白CD5都与前庭神经炎的发病有关.
  • 这些蛋白质代表了潜在的诊断生物标记物和VN的治疗点.
  • 对这些炎症途径的进一步研究可能会导致对VN的新临床干预措施.