尾神经内分泌瘤在尾切除术或右尾切除术后发生转移吗?
Taymeyah Al-Toubah1, Mintallah Haider1, Eleonora Pelle1
1Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL.
Journal of the National Comprehensive Cancer Network : JNCCN
|December 20, 2024
概括
第四期尾神经内分泌瘤 (NETs) 很少见,转移几乎总是同步发生. 在最初切除尾NET后,延迟转移性传播的风险是可以忽略不计的.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 内分泌学 在内分泌学.
背景情况:
- 尾神经内分泌瘤 (NETs) 经常在尾切除过程中偶然发现.
- 以前的研究表明,瘤转移的风险很小,瘤<2厘米.
- 人们仍然担心尾 NET 中晚期发病的转移,特别是在年轻患者中.
研究的目的:
- 调查尾NET患者转移的发生情况.
- 为了确定患有转移性尾NET的患者是否先前有早期诊断.
主要方法:
- 对一个大型神经内分泌瘤机构数据库的分析.
- 在各个阶段识别附属NET.
- 在转移性病例中评估疾病进展和初始表现.
主要成果:
- 在3795例胃肠道 (GEP) NET中,有124例是尾 NET.
- 只有10名患者 (0.3%) 患有第四期尾NET,其中8人被同步诊断.
- 两例转移性疾病患者在20年前有尾NET切除病史,但没有记录.
结论:
- 第四阶段的尾NET非常罕见,通常存在同步转移.
- 在切除局部尾NET后,转移性传播的风险是最小的.
- 完整的右半球切除术不推用于小于2厘米的瘤;它对较大的瘤的有用性是不确定的,术后监测几乎没有好处.
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