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身体不活动,抑郁症状和老年人发展为肉症:一项为期4年的纵向研究
Ryo Yamaguchi1, Keitaro Makino2, Osamu Katayama3
1Department of Preventive Gerontology, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan; Medical Science Division, Department of Medical Sciences, Graduate School of Medicine, Science and Technology, Shinshu University, Matsumoto, Nagano 390-8621, Japan.
身体不活动和抑郁症状一起显著增加了老年人肉症进展的风险. 解决这两个因素是预防的关键,因为没有一个单独显示出显著的关联.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 随着年龄增长而导致的肌肉损失 - - 萨尔科佩尼亚 (sarcopenia) 在老年人群中越来越令人担忧.
- 身体不活动和抑郁症状在老年人中很普遍.
- 这些因素对萨尔科佩尼亚进展的综合影响尚未完全理解.
研究的目的:
- 调查身体不活动和抑郁症状与肉类症进展的联合关联.
- 在社区居住的老年人中识别类病的危险因素.
主要方法:
- 这是一项为期四年的纵向研究,对日本2538名社区老年人进行了研究.
- 使用欧洲老年人肉症工作组2个标准进行肉症评估.
- 后勤回归分析以确定关联,对缺失数据进行多次归算.
主要成果:
- 4年后,20.4%的参与者发展为肉症.
- 身体不活动和抑郁症状的组显示了显著更高的萨尔科佩尼亚进展风险 (OR,1.64;95% CI,1.11-2.44).
- 无论是身体不活动还是单独的抑郁症状都没有与肉症的进展有显著的关联.
结论:
- 身体不活动和抑郁症状的同时存在是萨科佩尼亚进展的重要风险因素.
- 针对身体和心理健康的干预措施可能对预防老年人肉症至关重要.
- 为了有效地管理皮病,需要采用整体方法.
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