在精神药理学研究中使用经验采样方法:系统性审查
Davy Quadackers1, Fionneke Bos2, Johanna Hovenkamp-Hermelink2
1GGZ Drenthe Mental Health Institute, outpatient department, the Netherlands; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands.
Psychiatry research
|December 20, 2024
概括
经验采样方法 (ESM) 有助于评估精神病治疗的影响,特别是对物质使用和情绪障碍. 未来的研究可以使用ESM来个性化药物决策,但实施需要优化各种上下文因素.
科学领域:
- 精神病学是一个精神病学.
- 心理药理学 心理药理学
- 数字健康数字健康
背景情况:
- 经验采样方法 (ESM) 是评估精神病治疗治疗效果的宝贵工具.
- 之前的审查总结了ESM的实用性,需要更新和扩展分析.
研究的目的:
- 系统地审查和综合有关ESM在心理药理学研究中的使用的文献.
- 确定当前的研究主题,代表性不足的患者群体,以及未来ESM在精神病学中的应用领域.
主要方法:
- 在PubMed,PsycInfo和EMBASE数据库进行系统的文献搜索.
- 纳入标准:接受药物治疗的精神病患者,ESM提示≥2/day.
- 分析了79项研究,按疾病分类,并确定了关键研究主题.
主要成果:
- 大多数研究集中在物质使用 (47),情绪 (17) 和精神病障碍 (11) 上.
- 焦虑障碍,创伤后应激障碍和多动症的人数较少.
- 六个主要研究主题出现,包括治疗效果,症状波动,复发预测和ESM的附加值.
结论:
- 精神药理学主要使用ESM来监测治疗效果和症状波动.
- 未来的研究应该利用ESM进行个性化处方,针对老年患者和人格障碍患者等代表性不足的群体.
- 优化多层次的环境对于在临床实践中成功实施ESM至关重要.
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