可持续的抗微生物耐药性监测:是时候建立全球资金机制了
Chris Painter1, Direk Limmathurotsakul2, Tamalee Roberts3
1Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Mahosot Hospital, Vientiane, Laos; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
The Lancet. Infectious diseases
|December 20, 2024
概括
对抗生素耐药性 (AMR) 的监测对于资源较低的国家来说至关重要但代价昂贵. 持续的资金对于全球可持续的抗药性监测和控制工作至关重要.
科学领域:
- 全球卫生安全全球卫生安全
- 传染病流行病学 传染病流行病学
- 卫生经济学 卫生经济学
背景情况:
- 抗菌素耐药性 (AMR) 构成了未来的重大威胁,预计到2050年,其死亡率将超过其他主要传染病.
- 世界卫生组织关于AMR的全球行动计划强调加强监测和研究.
- 可持续的资金是维护AMR监测系统在低资源环境中的关键障碍.
研究的目的:
- 估计低收入和中等收入国家 (LMICs) 标准的国家抗菌耐药性监测系统的持续财务成本.
- 评估持续抗菌耐药性监测所需的国内公共卫生支出 (GGHE-D) 的比例.
- 突出需要一个长期的全球资金机制,用于AMR监测.
主要方法:
- 一个标准的国家AMR监测系统的成本估计.
- 对LMICs国内总体公共卫生支出 (GGHE-D) 的财务负担分析.
- 确定AMR监测成本超过GGHE-D的关键值的国家.
主要成果:
- 对于46个LMIC,AMR监测的估计成本超过了其总GGHE-D的2%.
- 在这些国家中,28个国家的成本超过了其总GGHE-D的5%.
- 这些财务需求表明当前国家融资模式的不可持续性.
结论:
- 在LMICs中维持国家AMR监测系统在财务上具有挑战性,如果没有外部支持,可能是不可持续的.
- 一个专门的长期全球融资机制是必不可少的,以确保 AMR 全球监测的连续性.
- 解决金融差距对于有效的全球抗菌药物耐药性控制战略至关重要.
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