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一个PDZ-酶性继电器介导了Par复合体调节器交换

Elizabeth Vargas1, Rhiannon R Penkert1, Kenneth E Prehoda1

  • 1Department of Chemistry and Biochemistry, Institute of Molecular Biology, 1229 University of Oregon, Eugene, Oregon, USA.

The Journal of biological chemistry
|December 20, 2024
PubMed
概括

对于细胞极化至关重要的Par复合体,使用非典型的蛋白激酶C (aPKC) 调节细胞膜. 这项研究揭示了Cdc42和Par-3与Par复合体的结合如何产生质继电器,控制其活性和细胞模式.

关键词:
这是一个PDZ域名.帕尔复杂的复杂的帕尔.亚洛斯特菌是什么意思?细胞极性是细胞的极性.蛋白质激酶酶是一种蛋白质激酶.

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