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Updated: Jun 4, 2025

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
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Published on: July 26, 2019

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伊诺西酸盐可以动态增强mTOR的稳定性,可溶性和催化活性

Lucia E Rameh1, John D York2, Raymond D Blind3

  • 1Department of Biochemistry and Molecular Biology, University of South Alabama, Mobile, Alabama, USA; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA; Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

The Journal of biological chemistry
|December 20, 2024
PubMed
概括

伊诺醇酸盐,包括伊诺醇基酸盐 (IP6),可以动态调节拉帕米辛 (mTOR) 激酶的机械标. 这些化合物增强了mTOR活性,并促进了更稳定的,可溶性活性状态,这证明了进一步的细胞研究是合理的.

关键词:
酶动力学 酶动力学伊诺西六基酸盐 伊诺西六基酸盐伊诺西酸盐和伊诺西酸盐的酸盐.激酶激酶的作用是什么运动学的动力学.在mTOROR中使用mTOR.mTOR复合体是一个复合体.信号传输 信号传输

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