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在肺动脉高血压风险分层的心声学参数的性别特异性差异

Nicola Benjamin¹, Veronika Schiffer¹, Carolin Resag¹

¹Centre for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

|December 20, 2024

概括

患有肺动脉高血压 (PAH) 的男性右心脏大小比女性大. 三环状平面缩外流 (TAPSE) /缩性肺动脉压 (sPAP) 是可靠的预测器的生存在PAH患者,无论性别.

科学领域:

心脏病学心脏病学
肺高血压是什么意思肺高血压
心声回声扫描 (Echocardiography) 是一种心声回声扫描.

背景情况:

在健康个体中,对右心脏功能的性别差异是已知的.
肺动脉高血压 (PAH) 影响心脏右侧的结构和功能.
心声学参数对于PAH风险分层至关重要.

研究的目的:

研究欧洲心脏病学会 (ESC) /欧洲呼吸学会 (ERS) 风险分层参数在PAH患者中的性差异.
评估这些性别差异对PAH生存估计的影响.

主要方法:

748名PAH患者的回顾性,横截面研究.
对右心房 (RA) 区域,右心室区域和三环状平面缩外流 (TAPSE) /缩肺动脉压力 (sPAP) 的评估.
多变量考克斯回归分析用于比较ESC/ERS风险分层值.

主要成果:

男人表现出明显更大的RA和右心室区域比女性 (P <.001).
在大多数世界卫生组织功能类和心脏指数风险组中,心脏大小的性别差异仍然存在.
与ESC/ERS值相比,索引值在年龄调整后生存分析中显示出更明显的差异.

结论:

这是第一个关于PAH中心声图右心脏大小性别差异的研究.
将RA面积与身体表面积的索引可能更好地反映身体成分,以进行风险分层.
在TAPSE/sPAP中没有显著的性别差异,这表明TAPSE/sPAP是PAH的强有力的预后因素.

关键词:

预测预后预测预测右心房区域的右心房区域.右心室区域的右心室区域.性差异性差异性差异性差异性差异性差异性差幸存的生存方式在TAPSE/sPAP中使用.

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