来自Hericium erinaceus多糖的提取,净化,结构特征,生物活动,修饰和应用:一篇综述
Ben Niu1, Lei Zhang1, Bodong Chen1
1Shaanxi University of Chinese Medicine, Xi'an 712046, Shaanxi, PR China.
International journal of biological macromolecules
|December 20, 2024
概括
的多糖 (HEPs) 显示出显著的健康益处,包括免疫支持和肠道保护. 研究强调了它们在医学和工业中的潜力,因为它们具有多样化的生物活动.
科学领域:
- 菌类学 菌类学是指菌类学.
- 药理学 药理学是指药理学的学科.
- 生物化学 生物化学
背景情况:
- 黑 (Hericium erinaceus) (牛) 是一种的动物. 个人 个人 个人 是一种具有丰富营养价值的药用真菌.
- 传统上在中国医学中用于肝脏,脏和消化系统的健康.
- 的多糖 (HEPs) 是具有广泛生物活性的关键活性化合物.
研究的目的:
- 对Hericium erinaceus多糖 (HEP) 的最新研究进行系统审查.
- 探索HEPs的提取,净化,结构,生物活性和应用.
- 突出HEP在食品,医药和工业领域的潜力.
主要方法:
- 关于过去五年发表的研究的文献综述.
- 对HEP的提取,净化和结构特征的研究分析.
- 对药理性质和结构-活性关系的体内和体外研究的评估.
主要成果:
- 高水平蛋白具有免疫调节,胃肠道保护,抗阿尔茨海默病和抗氧化作用.
- 免疫调节作用涉及TLR4/NFκB/MyD88/MAPK/PI3K/Akt路径.
- 高位蛋白调节肠道微生物群,具有免疫,抗炎和抗癌作用.
结论:
- 高血压药具有多样化的药理性质,具有显著的治疗潜力.
- 结构修改可以提高HEP的有效性和应用.
- 对HEP的进一步研究将推动各种行业的创新.
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