在胎盘组织中ToRCH病原体诱导的组织病理变化以及相关的产后并发症
Maryam Naseem1, Sanaullah Khan1, Dalal Sulaiman Alshaya2
1Institute of Zoological Sciences University of Peshawar Pakistan.
Acta tropica
|December 20, 2024
概括
在有不良产科病史 (BOH) 的女性中,ToRCH感染很常见,导致胎盘问题,如胆炎 (CV). 早期检测ToRCH病原体对于管理BOH和改善妊娠结果至关重要.
科学领域:
- 医学微生物学 医学微生物学
- 产科和妇科 产科和妇科
- 病理学 病理学 病理学
背景情况:
- 孕产妇感染的ToRCH (毒素菌,红疹病毒,细胞巨乳病毒,简单疹病毒) 感染与不良产科史 (BOH) 有关.
- 这些感染可以垂直传播,影响胎儿发育,导致妊娠并发症.
- 这项研究研究了ToRCH诱导的胎盘病理学变化及其与巴基斯坦妇女产科并发症的关联.
研究的目的:
- 调查患有BOH的女性中ToRCH感染的流行率.
- 为了确定与ToRCH感染相关的胎盘组织的组织病理变化.
- 确定ToRCH病原体与不良产科结果之间的相关性.
主要方法:
- 招募了83名女性进入实验 (BOH) 和对照组.
- 通过ELISA对TORCH抗体进行血液分析,通过PCR对TORCH核酸进行胎盘组织分析.
- 进行了胎盘组织的组织病理学检查,并使用描述性统计和千平方测试分析了数据.
主要成果:
- 总的ToRCH血清流行率为57.83%,在实验组 (53.01%) 和对照组 (4.81%) 显着更高.
- 在54.21%的实验组胎盘中检测到TORCH病原体;T. gondii和RV抗体是最常见的.
- 在实验组中有16.86%的患者观察到胆炎 (CV),特别是在那些有复发性自发性流产 (RSA) 患者中.
结论:
- 在患有BOH的女性中,TORCH病原体很普遍,特别是在巴基斯坦.
- 胆 ?? 炎 (CV) 是与BOH和ToRCH感染相关的主要组织病理学发现.
- 调查ToRCH感染对于管理女性患有RSAs等BOH并发症至关重要.
关键词:
抗体是一种抗体.不良的产科史 (BOH)胆 ?? 炎 (CV) 是一种在IgG IgG的基础上.的IgM IgM 的情况.核酸 (NA) 是一种核酸.胎盘组织的胎盘组织.在TORCH的病原体中.更多相关视频
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