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相关概念视频

Regulation of Expression at Multiple Steps01:23

Regulation of Expression at Multiple Steps

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The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the...
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Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

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Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
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Riboswitches01:56

Riboswitches

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Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
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Morphogenesis02:19

Morphogenesis

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Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
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Transcription01:10

Transcription

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Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
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Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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相关实验视频

Updated: Jun 4, 2025

Isolation and Transcriptome Analysis of Plant Cell Types
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通过植物相位分离进行表转录学调节.

Lisha Shen1

  • 1Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, 117604, Singapore; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, 117543, Singapore.

Trends in plant science
|December 20, 2024
PubMed
概括
此摘要是机器生成的。

像N6-甲基氨酸 (m6A) 这样的RNA修饰调节了基因表达. 通过组织RNA代谢,m6A驱动的相分离形成生物分子凝聚物,对植物发育和应激适应至关重要.

关键词:
生物分子凝聚剂是生物分子的凝聚物.副本转录组 (epitranscriptome) 是一个副本转录组.m(6) A6) 一个阶段分离的阶段分离.植物发展 植物发展压力反应应激反应

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科学领域:

  • 分子生物学分子生物学
  • 植物科学 植物科学
  • 遗传学 是一个遗传学.

背景情况:

  • 经转录体调节,特别是N6-甲基氨酸 (m6A) RNA修饰,增加了基因控制的复杂性.
  • 阶段分离和m6A相关生物分子凝聚物的形成越来越多地被认为是它们在植物RNA代谢中的作用.

研究的目的:

  • 要总结当前对m6A及其效应器如何调解生物分子凝结物形成的理解.
  • 阐明这些凝结物在植物发育和应激适应中的作用.

主要方法:

  • 关于植物m6A表转录学和相分离的当前文献的综述.
  • 对与m6A相关的生物分子凝聚物的拟议模型的分析.

主要成果:

  • m6A的修改影响了生物分子凝聚物的组装.
  • 这些凝结物充当RNA代谢的调节枢纽,影响植物生长和对环境挑战的反应.
  • m6A效应器在凝结物的形成和功能中发挥着关键作用.

结论:

  • m6A介导的相分离是调节植物RNA代谢的关键机制.
  • 生物分子凝聚物是集成表体转录信号的动态平台,用于控制植物发育和应激适应.
  • 对m6A相关的冷凝剂的进一步研究有望为了解植物弹性提供希望.