在地中海中等和高风险人口中,心电图和心血管风险的主要异常
Joan Pou Bordoy1, Alfonso Leiva2, Maria José Albendín Ariza3
1Centre de Salut de Camp Redó, Gerència d'Atenció Primària de Mallorca, Servei de Salut de les Illes Balears (IB-SALUT), Mallorca, Islas Baleares, España; Institut d'Investigació Sanitària de les Illes Balears (IdISBa), Mallorca, Islas Baleares, España.
主要心电图异常 (MECG) 是常见的,并且可以独立预测心血管事件 (CVE). 然而,在本研究中,MECG并没有改善超过已确定的心血管风险因素 (CVRF) 的风险预测.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 电心电图是指心电图.
背景情况:
- 主要心电图异常 (MECG) 在中年和老年人中普遍存在.
- MECG可以作为心血管事件 (CVE) 的重要预测指标.
研究的目的:
- 调查MECG (明尼苏达分类) 和CVE之间的关联,独立于传统的心血管风险因素 (CVRF).
- 通过西班牙冠状动脉事件风险函数 (FRESCO) 确定MECG是否可以提高心血管风险预测.
主要方法:
- 分析了来自PREDIMED研究的1752名参与者 (年龄在55-80岁之间),他们的CVRF中等至高.
- 平均随访时间为5.1年,评估了累计的CVE发病率和按性别的危险比率.
- 利用多变量考克斯回归和统计措施,包括哈雷尔的C指数和重新分类改进.
主要成果:
- 25%的参与者在基线时表现出MECG.
- MECG显示与CVE的发生有显著的关联.
- 特定的MECG发现,如LVH,心房动和ST段抑郁,与男性和女性的CVE风险增加有关.
结论:
- MECG独立地与心血管事件有关.
- 当考虑传统的风险因素时,MECG并不能显著改善心血管风险预测.
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