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Updated: Jun 4, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Published on: November 28, 2017

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通过有限的蛋白质分解与质谱学相结合,探索蛋白质构造

Chloé Van Leene1, Laura Van Moortel1, Karolien De Bosscher1

  • 1Vlaams Instituut voor Biotechnologie (VIB) Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.

Trends in biochemical sciences
|December 20, 2024
PubMed
概括

与质谱学 (LiP-MS) 相结合的有限蛋白质解提供了对蛋白质结构和疾病的洞察力. 进步提高了其在药物研究中的使用,尽管蛋白质提取和鉴定方面的挑战仍然存在.

关键词:
形状的变化 形状的变化符合类型的酸.有限的蛋白质溶解.质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量结构蛋白质组学 结构蛋白质组学

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