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手术性死性肠球炎的早产新生儿的短期术后并发症:一个多中心的回顾性队列研究
Adinda G H Pijpers1,2,3, Ceren Imren4, Otis C van Varsseveld5
1Department of Pediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. a.pijpers1@amsterdamumc.nl.
Pediatric surgery international
|December 20, 2024
概括
在早产婴儿的瘤性肠球炎 (NEC) 手术有57.1%的并发症率. 手术前的心血管支持增加了主要并发症,而静脉形成与轻微并发症有关.
科学领域:
- 新生儿手术 新生儿手术
- 儿科外科手术 儿科外科手术
- 胃肠病学 胃肠病学
背景情况:
- 超过一半的早产新生儿患有死角性肠球炎 (NEC) 需要手术.
- 了解短期术后结果和并发症率对于NEC管理至关重要.
研究的目的:
- 为提供NEC的30天术后并发症的概述.
- 为了确定轻微和重大短期术后并发症的危险因素.
主要方法:
- 对早产婴儿 (GA<35周) 进行了回顾性研究,这些婴儿接受了NEC (2008-2022) 手术治疗.
- 使用克拉维恩-蒙达蒂分类得分的并发症.
- 通过多变量逻辑回归分析的风险因素.
主要成果:
- 包括326名患者,204名患者患有静脉,80名患者患有主性静脉,32名患者患有两种病.
- 手术后死亡率为19.0%.
- 整体并发症率为57.1% (186名患者),其中118例主要并发症和68例轻微并发症. 败血症 (19.4%),口腔相关问题 (13.3%) 和伤口脱光 (11.3%) 是最常见的.
- 手术前的心血管支持 (OR 1.92) 和静脉形成 (OR 6.73) 分别是主要和轻微并发症的重要危险因素.
结论:
- 在NEC手术后的术后并发症率为57.1%.
- 心血管支持和静脉形成分别是主要和轻微并发症的确定的危险因素.
- 调查结果有助于改善有关NEC结果的家长咨询.
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