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Updated: Jun 4, 2025

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SS18-SSX驱动TYK2表达以激活STAT3/Bcl2轴,促进细胞亡逃避和促进突肉瘤进展

Wenjing Qin1,2, Changliang Peng3, Xianhe Yang2

  • 1The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.

Cell biology and toxicology
|December 20, 2024
PubMed
概括

准氨酸激酶2 (TYK2) 可能会诱导突肉瘤 (SS) 中的亡. 这项研究揭示了由SS18-SSX驱动的TYK2 / STAT3 / Bcl2通路,通过逃避亡来促进SS细胞的进展.

关键词:
避开亡的方法这是SS18-SSXX.在STAT3/Bcl2轴上突肉瘤 (Synovial Sarcoma) 是一个突肉瘤.这就是TYK2TYK2.

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