在典型的卵巢皮质病变中,作为恶性转变风险的尺寸门:一个范围审查
Haidey Jordan1, Gavin Low2, Mitchell P Wilson2
1University of Alberta, Edmonton, Canada. jhaidey@ualberta.ca.
Abdominal radiology (New York)
|December 20, 2024
概括
10厘米的O-RADS值可能错误地分类恶性卵巢皮质囊. 超过25%的恶性转变发生在小于10厘米的囊中,这表明需要修订风险评估.
科学领域:
- 妇科瘤学 妇科瘤学
- 放射学 放射学是一门学科.
- 病理学 病理学 病理学
背景情况:
- 对于卵巢皮质囊的O-RADS (卵巢附报告和数据系统) 恶性瘤风险分层,目前使用10厘米的值.
- 这一门是基于专家的共识,而不是关于恶性转变风险的客观临床数据.
研究的目的:
- 对评估卵巢皮质囊大小和恶性转变风险的研究进行全面的范围审查.
- 评估目前10厘米O-RADS值对恶性瘤风险分层的充分性.
主要方法:
- 从创立到2024年1月14日,对MEDLINE,Embase,Scopus和Cochrane图书馆数据库进行系统审查.
- 包括病例报告和评估皮质囊大小和恶性转变的病理标准的系列.
- 根据PRISMA-ScR指南进行定性数据综合,包括灰色文献和参考列表搜索.
主要成果:
- 包括25项研究 (6个案例报告,19个回顾性研究) 涉及15295个皮质囊.
- 在215个病变中发生恶性转变,其中46% (27%) 的病变小于10厘米.
- 报告时,固体增强元件都大于1厘米.
结论:
- 目前的10厘米O-RADS值可能错误地将超过25%的恶性皮质囊归类为"几乎肯定是良性的".
- 应该考虑修改O-RADS指南,可能包括加强对固体成分囊的监测或妇科瘤学家转诊.
- 目前的指导方针可能需要调整,以提高对卵巢皮质囊恶性瘤风险分层的敏感性.
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