在老年人中无症状结核病的比例:系统性审查和元分析
Yiqing Zhou1, Fei Wang2, Songhua Chen2
1School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
BMC public health
|December 20, 2024
概括
结核病 (TB) 在老年人中很常见,许多人没有症状. 活跃病例发现显示,67.7%的老年结核病患者无症状,强调需要有针对性的查计划.
科学领域:
- 老年学是一门学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 老年人是结核病 (TB) 的脆弱人群.
- 在老年人中,大量结核病例无症状.
- 积极的病例发现对于在这个人口群体中识别结核病至关重要.
研究的目的:
- 确定在活跃结核病的老年患者中无症状结核病的患病率.
- 分析影响老年人无症状结核病比例的因素.
主要方法:
- 在2023年12月之前对多个数据库进行系统的文献搜索.
- 使用医疗保健研究和质量标准的机构对包括的研究进行质量评估.
- 用异质性评估进行的元分析 (I2统计,Q测试),子组分析,敏感性分析,元回归和出版偏差测试 (贝格,埃格).
主要成果:
- 分析了9项研究,其中包括364260名老年人.
- 在老年人中,无症状结核病的总体比例为67.7% (95%CI:54.7-79.5%).
- 无症状结核病的比例在高负担国家 (66.3%) 和多种查策略的国家 (67.6%) 较高;在2019年后的研究中 (54.3%) 和大样本大小的国家 (62.3%) 减少.
结论:
- 高比例的老年人患有无症状结核病.
- 大规模查对于在老年人中检测活跃结核病例至关重要.
- 研究结果可以为公共卫生政策提供信息,以减少老年人结核病负担.
更多相关视频
06:26Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
Published on: July 28, 2023
2.1K
09:34An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
1.8K
相关概念视频
Pulmonary Tuberculosis II
211
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
211
Pulmonary Tuberculosis I
220
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
220
Pulmonary Tuberculosis IV
133
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
133
Pulmonary Tuberculosis V
170
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
170
Pulmonary Tuberculosis III
303
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
303
