中年和老年人肺通风功能与认知功能之间的关联:来自中国西南地区的一项观察性研究
Xu Li1, Lin Li1, Shuming Ji1
1Department of Clinical Research and Management, Center of Biostatistics, Design, Measurement and Evaluation (CBDME), West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, P. R. China.
BMC pulmonary medicine
|December 20, 2024
概括
肺透气功能障碍,特别是阻塞性类型,在中国西南地区很常见,并且与老年人轻度认知障碍风险增加有关. 建议对肺部健康进行评估,以改善认知功能.
科学领域:
- 肺部医学 肺部医学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 在中国西南地区普遍存在.
- 这个地区的老年人的认知功能超过了全国平均水平.
- 这项研究调查了肺呼吸功能及其与轻度认知障碍 (MCI) 的联系.
研究的目的:
- 评估中国西南地区中老年人和老年人的肺通风功能.
- 为了确定肺透气功能障碍是否是该人群中MCI的危险因素.
主要方法:
- 在中国西南 (2019-2021) 进行的一项队列研究包括2,337名参与者.
- 螺旋计测量了肺功能;迷你精神状态检查评估了认知功能.
- 多重后勤回归分析了肺功能和认知水平之间的关联.
主要成果:
- 41.16%的参与者患有肺呼吸功能障碍,主要是轻度阻塞型 (COPD:14.21%).
- 肺呼吸功能 (PPF) 较差与患MCI的风险较高有关 (OR:1.38;P=0.026).
- 肺呼吸功能障碍的严重程度与MCI风险增加相关 (趋势P=0.009).
结论:
- 肺功能,特别是阻塞性功能障碍,是中国西南地区老年人关注的问题.
- 肺部健康评估应纳入日常护理,以改善肺部和认知健康.
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