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Updated: Jun 4, 2025

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在结直肠癌中,Wnt/β-catenin通路是治疗耐药性驱动的上皮质-介质细胞过渡和干性之间的联系

Murilo Ramos Rocha1, Yuri Kelly Castillo-Medina1, Bárbara Martins de Lima Coelho1

  • 1Cellular and Molecular Oncobiology Program, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil.

Cell biology international
|December 21, 2024
PubMed
概括

Wnt/β-catenin通路促进癌症干和上皮-介质细胞过渡 (EMT),增加治疗耐药性. 抑制这种途径可能会阻止来自EMT细胞的癌症干细胞的发展,改善结直肠癌的治疗方法.

关键词:
在Wnt/β-catenin路径中.表皮细胞-介质细胞过渡.树干性 树干性治疗耐药性 治疗耐药性

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