急性摄入yerba mate (ilex paraguariensis) 输液不会改变内皮功能,血液动力学或心率变化:一个随机交叉临床试验
Richard Emanuel Filipini1, Manuela de Faria Barcellos José1,2, Guilherme Fleury Fina Speretta3,4
1Department of Physiological Sciences, Biological Sciences Center, Federal University of Santa Catarina - Rua da Prefeitura Universitária, Córrego Grande, Florianópolis, SC, 88037-000, Brazil.
Plant foods for human nutrition (Dordrecht, Netherlands)
|December 21, 2024
概括
在健康的成年人中,yerba mate (YM) 输液没有急性影响内皮功能,血液动力学或心率变化. YM输液的温度没有改变这些心血管参数.
科学领域:
- 心血管健康 心血管健康
- 草药研究 草药研究
- 人体生理学 人体生理学
背景情况:
- 心血管疾病 (CVD) 构成了严重的健康负担.
- 草本植物正在被探索,因为它们有可能减轻心血管疾病风险.
- 耶巴马特 (YM),具有抗氧化和抗炎性质,是改善心血管健康标志物的候选者.
研究的目的:
- 为了研究Yerba mate (YM) 输液对内皮功能的急性影响.
- 评估YM对血液动力学参数和心率变化 (HRV) 的影响.
- 为了确定YM的温度 (热或冷) 是否会影响这些心血管结果.
主要方法:
- 一个交叉随机临床试验,涉及13名健康成年人 (18-40岁).
- 参与者在三个条件下进行了评估:对照 (水),冷YM输液和热YM输液.
- 在干预之前和之后测量了内皮功能 (流介导扩张-口腔疾病),血压 (血压),心率 (HR) 和HRV.
主要成果:
- 对于口病 (p < 0.05) 观察到显著的干预效应,冷和热YM与对照组相比显示出更高的口病%.
- 对于口病,没有发现显著的时间或时间*干预效应.
- 虽然观察到BP,HR和HRV的时间效应,但对于这些参数没有观察到干预效应或时间*干预相互作用.
结论:
- 无论温度如何,急性摄入yerba mate输液对健康成年人的内皮功能,中央血液动力学或自主性参数没有显著影响.
- 需要进一步的研究来探索急性和慢性Yerba mate消费对内皮功能的剂量反应关系.
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