母亲精神分裂症与儿童严重喘恶化风险之间的关联
J G Pouget1, E Cohen2, J G Ray3
1Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
这项研究发现,母亲患有精神分裂症的儿童喘恶化没有显著增加. 这项研究检查了加拿大大众中的喘住院和急诊室的住院情况.
科学领域:
- 儿科医学 儿科医学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 母亲精神分裂症与儿童慢性疾病有关.
- 关于精神分裂症母亲的孩子急性喘恶化情况的数据有限.
研究的目的:
- 评估母亲精神分裂症与儿童喘恶化风险之间的关联.
- 评估与喘相关的住院和急诊室访问情况.
主要方法:
- 基于人口的研究,使用来自加拿大安大略省的健康数据.
- 一组385,989名儿童被诊断患有喘.
- 将患有母亲精神分裂症的儿童 (n=1407) 与没有精神分裂症的儿童 (n=384,582) 进行比较.
- 分析了使用考克斯比例危险模型和安德森-吉尔回归的第一次和复发性喘恶化.
主要成果:
- 对喘恶化急性护理的利用没有观察到任何有意义的差异.
- 第一次住院 (1.21) 和急救诊所 (1.06) 的调整后危险比率在统计学上并不显著.
- 再次住院 (1.27) 和急救诊所 (1.11) 的调整率比率也没有显著差异.
结论:
- 该研究没有发现母亲精神分裂症与儿童急性喘恶化风险增加之间存在显著的关联.
- 研究结果表明,母亲的精神分裂症对后代的急性喘护理需求没有实质性的影响.
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