基于绿色溶剂的液相微提取技术的最新进展,用于对传统中医药中活性成分进行染色学分析
Li-Zhu Zhao1, Hui-Ling Cao1, Zhi-Qiang He2
1College of Pharmacy, Harbin University of Commerce, Harbin 150076, China.
Journal of chromatography. A
|December 21, 2024
概括
液相微提取 (LPME) 技术提供了提取传统中医药 (TCM) 活性成分的先进方法. 新的绿色溶剂增强了分析复杂的TCM样本的这些技术.
科学领域:
- 分析化学 分析化学
- 药理学 药理学是指药理学的学科.
- 绿色化学 绿色化学
背景情况:
- 传统中医 (TCM) 含有众多化合物,使得活性成分的提取具有挑战性.
- 了解TCM疗效需要阐明机制,因为复杂的矩阵和微量化合物阻碍了这一过程.
- 液相微提取 (LPME) 已成为从TCM中分离活性成分的关键技术.
研究的目的:
- 为分析TCM中的活性成分提供LPME技术的全面审查.
- 总结新型绿色溶剂及其在LPME中用于TCM分析的应用.
- 评估各种LPME方法和绿色溶剂的原则,参数,优点和缺点.
主要方法:
- 关于液相微提取 (LPME) 技术的文献综述.
- 分析单滴微提取 (SDME),空腔纤维液相微提取 (HF-LPME),分散液液微提取 (DLLME) 和电膜提取 (EME).
- 绿色溶剂的比较,包括深层环氧溶剂,离子液体和超分子溶剂.
主要成果:
- 各种基于绿色溶剂的LPME方法对TCM分析具有前景.
- LPME技术可以有效地从复杂的TCM矩阵中提取活性成分.
- 不同的绿色溶剂在特定应用中具有独特的优点和缺点.
结论:
- LPME技术,特别是使用绿色溶剂的技术,对TCM研究有价值.
- 这些先进的样品预处理方法有助于分析TCM中的活性成分.
- 未来的研究应该专注于优化LPME方法,并探索用于TCM应用的新型绿色溶剂.
更多相关视频
07:16Preparation of Gynura bicolor DC samples for High-Resolution Tandem Mass Spectrometry
Published on: February 2, 2024
496
09:24Standardized Identification of Compound Structure in Tibetan Medicine Using Ion Trap Mass Spectrometry and Multiple-Stage Fragmentation Analysis
Published on: March 17, 2023
829
相关概念视频
Supercritical Fluid Chromatography
209
Supercritical fluid chromatography (SFC) provides a beneficial substitute for gas chromatography (GC) and liquid chromatography (LC) for certain samples because it merges the top attributes of both techniques. SFC allows the separation and analysis of compounds that GC or LC does not easily manage. These compounds are traditionally nonvolatile or thermally unstable, making GC unsuitable and lacking functional groups required for HPLC analysis.
SFC utilizes a supercritical fluid mobile phase,...
SFC utilizes a supercritical fluid mobile phase,...
209
High-Performance Liquid Chromatography: Elution Process
423
In High-Performance Liquid Chromatography (HPLC), the elution process is critical to the separation of analytes and the quality of chromatographic results. Elution describes how compounds move through the column and separate based on their interactions with the mobile and stationary phases. This process determines the resolution, peak shape, and retention times in the chromatogram, which are essential for identifying and quantifying components in complex mixtures. Understanding the elution...
423
